Floxin (ofloxacin) is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body. Floxin is used to treat bacterial infections of the skin, lungs, prostate, or urinary tract (bladder and kidneys). Floxin is also used to treat pelvic inflammatory disease and chlamydia and/or gonorrhea. This medication is used to treat a variety of bacterial infections. Ofloxacin belongs to a class of drugs called quinolone antibiotics.